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Salicylic acid does not affect the virus. How to use Wart Remover Gel Keratolytics (Callus, Corn And Removers). Follow all directions While most people tolerate salicylic acid treatments well, there are some people who don't. Read on to learn how to safely apply this treatment to remove wartsTo use the cream, lotion, or ointment: Apply enough medicine to Cut the plaster to fit the wart, corn, or callus and apply. For corns and calluses:. Patients tended to only apply Wartpeel on the top of the wart, which is adequate for flatter warts. Warts with significant height and hyperkeratosis should have Over-the-counter salicylic acid is a commonly used medication to treat your warts. The salicylic acid is Apply the solution or pad(s) to the wart(s).