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Diagnosis and Management of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline Update from the ACP, ACCP, ATS, ERS (2011). Ann Intern Australian and New Zealand Guidelines for the management of Chronic Obstructive Pulmonary Disease. donate · shop · Full COPD-X GuidelinesHow should I treat a person with an acute exacerbation of COPD who does not require admission? · Amoxicillin 500 mg three times a day for 5 days. · Doxycycline An acute exacerbation of chronic obstructive pulmonary disease (COPD) typically presents with an increased level of dyspnea, worsening of chronic cough, COPD patients that meet the criteria for lung cancer risk assessment. Such patients may report exacerbations of respiratory symptoms or even.