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glucosamine sulphate and glucosamine hydrochloride. NICE Guideline CG177: Osteoarthritis: care and management. 1. , states that:. Evidence: • NICE Clinical Guidance (CG 59) for Osteoarthritis2 states that the use of glucosamine or chondroitin products is not recommended for the treatmentDo not offer glucosamine or chondroiton products for the management of osteoarthritis. Interventions: Glucosamine. Source guidance details. Guidance: The use of glucosamine products is not recommended for the treatment of osteoarthritis. Guidance: Osteoarthritis (CG59); Published date: February 2008 Experts' Recommendations. Experts disagree on whether glucosamine and chondroitin may help knee and hip osteoarthritis. The American College of Rheumatology