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Generic Name : Nabumetone. Pronunciation : nab-UE-me-tone. Latest prescription information about Nabumetone. Learn how to pronounce the drug's name, Nabumetone oral tablet is a prescription medication used to help reduce pain, inflammation, and swelling caused by osteoarthritis and rheumatoid arthritis. Adults—At first, 1000 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 2000 mg per day. Approximately 35% of a 1,000-mg oral dose of nabumetone is converted to 6MNA and 50% Advanced Renal Disease: No information is available from controlledGet medical help right away, if you have any of the symptoms listed above. The most common side effects of Relafen include: stomach pain,; indigestion,; nausea, Find patient medical information for nabumetone oral on WebMD including its uses, Dosage is based on your medical condition and response to treatment. Osteoarthritis. 1000 mg PO once daily initially; maintenance: 1000-2000 mg/day PO in single daily dose or divided q12hr; not to exceed 2000 mg/day Nabumetone: learn about side effects, dosage, special precautions, and more on MedlinePlus.