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How to perform Manual Differential Count · Focus the microscope on the 10X objective (low power). · Examine the peripheral edge of the smear. · If the smear is The lab specialist then counts the number of each white blood cell type. The specialist may do a manual blood count, visually identifying the number and size ofPerform a differential leukocyte count: This is usually done on 100 leukocytes. When you have finished your scanning and have found the area of the smear where