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Many judgements are required in the process of preparing a Cochrane review or meta-analysis. Sensitivity analyses should be used to examine whether overall If the results of the individual studies are combined to produce an overall statistic, this is usually called a meta-analysis. Many Cochrane Reviews measureMeta-analysis is the statistical combination of results from two or more separate Cochrane Handbook for Systematic Reviews of Interventions version 6.2 individual patient data, prospective meta-analysis, and qualitative research). The list of all author contributors of the Handbook is available here. Cochrane Handbook for Systematic Reviews of Interventions version 6.2 (updated 12.2 Statistical synthesis when meta-analysis of effect estimates is not