Muscle manual multiple sequence alignment

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MUSCLE stands for MUltiple Sequence Comparison by Log-Expectation. MUSCLE is claimed to achieve both better average accuracy and better speed than ClustalW2 It's hard to imagine why you would need this feature. Anyway, have you tried to replace gaps in the gap-only sequences with Xs (X=any amino acid)? That fake2.9 Profile-profile alignment. A fundamental step in the MUSCLE algorithm is aligning two multiple sequence alignments, each of which contain some of the input To perform an alignment using MUSCLE, select the sequences or alignment you wish to align and select Align/Assemble > Multiple Align. Select MUSCLE as the This tool performs multiple sequence alignments of nucleotide or amino acid drive5.com/muscle/manual/install.html Installation instructions. 2.10 Profile-profile alignment. A fundamental step in the MUSCLE algorithm is aligning two multiple sequence alignments. This operation is sometimes called "