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Intra-articular hyaluronan injections are not recommended for the treatment of osteoarthritis. NICE Pathways · NICE guidance · Life sciences · Standards and Manufacturers advise avoid—no information available. Monitoring requirements. Monitoring of patient parameters. Monitor blood-glucose concentration before glucosamine sulphate and glucosamine hydrochloride. NICE Guideline CG177: Osteoarthritis: care and management. 1. , states that:. Do not offer glucosamine or chondroiton products for the management of osteoarthritis. Interventions: Glucosamine. Source guidance details. Guidance: Experts' Recommendations. Experts disagree on whether glucosamine and chondroitin may help knee and hip osteoarthritis. The American College of RheumatologyEvidence: • NICE Clinical Guidance (CG 59) for Osteoarthritis2 states that the use of glucosamine or chondroitin products is not recommended for the treatment