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Caring for Young Women. Who Are at High Risk for. EArly-OnSET. BrEAST CAnCEr. A Summary of Screening, Counseling, and Testing Guidelines. The ACS made a qualified recommendation that women should have the opportunity to begin screening at age 40 years and a strong recommendation that women should Screening Guidelines for Women at Average Breast Cancer Risk · Women between the ages of 25 and 40 should have an annual clinical breast examination. · Women 40 The NCCN recommends screening with mammography plus breast MRI for some women at higher risk of breast cancer, including those with [144-145]:. A BRCA1 or BRCA2