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How many somas can i take at one time

2022.01.07 19:35




















Data over many decades of carisoprodol use in pregnancy have not identified a drug-associated risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes. Data on meprobamate, the primary metabolite of carisoprodol, also do not show a consistent association between maternal use of meprobamate and an increased risk of major birth defects see Data.


In a published animal reproduction study, pregnant mice administered carisoprodol orally at 2. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U. Retrospective case-control and cohort studies of meprobamate use during the first trimester of pregnancy have not consistently identified an increased risk or pattern of major birth defects.


For children exposed to meprobamate in-utero, one study found no adverse effect on mental or motor development or IQ scores. Data from published literature report that carisoprodol and its metabolite, meprobamate, are present in breastmilk.


There are no data on the effect of carisoprodol on milk production. There is one report of sedation in an infant who was breastfed by a mother taking carisoprodol see Clinical Considerations. The efficacy, safety, and pharmacokinetics of SOMA in pediatric patients less than 16 years of age have not been established.


The efficacy, safety, and pharmacokinetics of SOMA in patients over 65 years old have not been established. The safety and pharmacokinetics of SOMA in patients with renal impairment have not been evaluated. Carisoprodol is dialyzable by hemodialysis and peritoneal dialysis. The safety and pharmacokinetics of SOMA in patients with hepatic impairment have not been evaluated.


Patients with reduced CYP2C19 activity have higher exposure to carisoprodol. Carisoprodol has been subject to abuse, misuse, and criminal diversion for nontherapeutic use [ see Warnings and Precautions 5. Abuse of carisoprodol poses a risk of overdosage which may lead to death, CNS and respiratory depression, hypotension, seizures and other disorders [ see Warnings and Precautions 5.


Patients at high risk of SOMA abuse may include those with prolonged use of carisoprodol, with a history of drug abuse, or those who use SOMA in combination with other abused drugs. Prescription drug abuse is the intentional non-therapeutic use of a drug, even once, for its rewarding psychological effects. Drug addiction, which develops after repeated drug abuse, is characterized by a strong desire to take a drug despite harmful consequences, difficulty in controlling its use, giving a higher priority to drug use than to obligations, increased tolerance, and sometimes physical withdrawal.


Drug abuse and drug addiction are separate and distinct from physical dependence and tolerance for example, abuse or addiction may not be accompanied by tolerance or physical dependence [ see Drug Abuse and Dependence 9. Physical dependence is characterized by withdrawal symptoms after abrupt discontinuation or a significant dose reduction of a drug.


Both tolerance and physical dependence have been reported with the prolonged use of SOMA. Reported withdrawal symptoms with SOMA include insomnia, vomiting, abdominal cramps, headache, tremors, muscle twitching, anxiety, ataxia, hallucinations, and psychosis. Serotonin syndrome has been reported with carisoprodol intoxication. Many of the carisoprodol overdoses have occurred in the setting of multiple drug overdoses including drugs of abuse, illegal drugs, and alcohol.


The effects of an overdose of carisoprodol and other CNS depressants e. Basic life support measures should be instituted as dictated by the clinical presentation of the SOMA overdose.


Vomiting should not be induced because of the risk of CNS and respiratory depression, and subsequent aspiration. Circulatory support should be administered with volume infusion and vasopressor agents if needed. Seizures should be treated with intravenous benzodiazepines and the reoccurrence of seizures may be treated with phenobarbital. In cases of severe CNS depression, airway protective reflexes may be compromised and tracheal intubation should be considered for airway protection and respiratory support.


For decontamination in cases of severe toxicity, activated charcoal should be considered in a hospital setting in patients with large overdoses who present early and are not demonstrating CNS depression and can protect their airway.


SOMA carisoprodol Tablets are available as mg and mg round, white tablets. Carisoprodol is a white, crystalline powder, having a mild, characteristic odor and a bitter taste.


It is slightly soluble in water; freely soluble in alcohol, in chloroform, and in acetone; and its solubility is practically independent of pH. Carisoprodol is present as a racemic mixture. The structural formula is:. Other ingredients in the SOMA drug product include alginic acid, magnesium stearate, potassium sorbate, starch, and tribasic calcium phosphate.


The mechanism of action of carisoprodol in relieving discomfort associated with acute painful musculoskeletal conditions has not been clearly identified. In animal studies, muscle relaxation induced by carisoprodol is associated with altered interneuronal activity in the spinal cord and in the descending reticular formation of the brain.


Carisoprodol is a centrally acting skeletal muscle relaxant that does not directly relax skeletal muscles. A metabolite of carisoprodol, meprobamate, has anxiolytic and sedative properties.


The degree to which these properties of meprobamate contribute to the safety and efficacy of SOMA is unknown. The pharmacokinetics of carisoprodol and its metabolite meprobamate were studied in a crossover study of 24 healthy subjects 12 male and 12 female who received single doses of mg and mg SOMA see Table 2. The exposure of carisoprodol and meprobamate was dose proportional between the mg and mg doses.


The Cmax of meprobamate was 2. Absolute bioavailability of carisoprodol has not been determined. The mean time to peak plasma concentrations Tmax of carisoprodol was approximately 1. Co-administration of a high-fat meal with SOMA mg tablet had no effect on the pharmacokinetics of carisoprodol.


Carisoprodol is used for short-term treatment. If you stop taking this drug suddenly, you may have withdrawal symptoms. These can include sleep problems, vomiting, stomach pain, headache, or shakiness and muscle twitching. For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body. This risk is higher if this medication is used with several drugs that are misused or taken in overly high doses.


Symptoms of an overdose of this drug can include:. If your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose.


Never try to catch up by taking two doses at once. This could result in dangerous side effects. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:. Not every pharmacy stocks this drug.


When filling your prescription, be sure to call ahead to make sure they carry it. You may need to have blood tests to check your kidney and liver function while you take this drug. The cost of these tests will depend on your insurance coverage. Many insurance companies require a prior authorization for this drug.


This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.


However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.


The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Methocarbamol Robaxin is an oral medication used to treat muscle pain and stiffness.


Learn about side effects, warnings, dosage, and more. If your muscles start becoming sore one to two days after exercising, you may be experiencing delayed onset muscle soreness DOMS. This type of…. Tendinitis results in pain that makes it difficult to move the affected joint. Not all muscle soreness is the same.


Acute muscle soreness is felt during or immediately after exercise. With delayed onset muscle soreness, your…. The half-life of carisoprodol is about 1 to 3 hours, which varies depending on individual metabolism. The half-life of meprobamate is much longer, between 6 and 17 hours, which can lead to accumulation with multiple doses. Both carisoprodol and its metabolite meprobamate are excreted in the urine and can be detected for several days after the last dose.


To prevent side effects and drug interactions, be sure to discuss all prescription and nonprescription medications you are taking or plan to take with your doctor. Your metabolism of Soma can be affected if you have ever had liver or kidney disease. If you are pregnant, breastfeeding, or plan to become pregnant, discuss with your doctor what the implications may be for taking Soma.


Soma can make you drowsy, so it's important to take precautions for driving or operating machinery. Side effects can include headache, fast heartbeat, drowsiness, confusion, slowed thinking, upset stomach, skin rash, and sluggish movements. Soma should be taken exactly as directed. To avoid the following severe side effects, do not take more than prescribed or take it more often than directed by your healthcare provider.


Contact your doctor immediately or call if you have any of these symptoms. In very large doses, Soma will produce a meprobamate overdose, which can lead to a coma. When you stop taking Soma, duration and severity of withdrawal symptoms will depend on how long the drug has been used, the level of tolerance, and the dosage.


If you abruptly stop taking Soma, you may experience short-term withdrawal symptoms that can begin 12 to 24 hours after your last dose and usually resolve within 2 to 4 days.


Carisoprodol and meprobamate can be detected on a screen for prescription or over-the-counter drugs in blood and urine, as may be done in the case of a suspected overdose.


They typically aren't included in a urine drug screen such as done for employment. However, if you are taking the combination product that includes codeine, that will be detected. Be sure to disclose your medications to the testing lab so they are able to better interpret the test results.


Learn the best ways to manage stress and negativity in your life. Highlights of prescribing information. Soma carisoprodol tablets for oral use, CIV.