How many people get hodgkin lymphoma a year

Leukemia, lymphoma and myeloma are expected to cause the deaths of an estimated 57, people in the US in These diseases are expected to account for 9.

Leukemia New Cases In , 61, people are expected to be diagnosed with leukemia. Prevalence An estimated , people are living with or in remission from leukemia in the US. Survival The 5-year relative survival rate for leukemia has more than quadrupled, from 14 percent in whites from to the only data available to From to , the five-year relative survival rates overall were ALL — Deaths Approximately 23, deaths 13, males and 9, females in the US are expected to be attributed to leukemia in From to , leukemia was the sixth most common cause of cancer deaths in males and the seventh most common cause of cancer deaths in females in the US.

The lymphatic system is part of your immune system. Clear fluid called lymph flows through the lymphatic vessels and contains infection-fighting white blood cells, known as lymphocytes. In Hodgkin lymphoma, B-lymphocytes a particular type of lymphocyte start to multiply in an abnormal way and begin to collect in certain parts of the lymphatic system, such as the lymph nodes glands.

The affected lymphocytes lose their infection-fighting properties, making you more vulnerable to infection. The most common symptom of Hodgkin lymphoma is a painless swelling in a lymph node, usually in the neck, armpit or groin. Read more about the symptoms of Hodgkin lymphoma.

Also shown is primary cancer in the lymph nodes and a pullout of the brain with cerebrospinal fluid. Used with Permission. Contact artist at www. Lymphoma external icon is a general term for cancers that start in the lymph system the tissues and organs that produce, store, and carry white blood cells that fight infections.

The two main kinds of lymphoma are—. Non-Hodgkin lymphoma becomes more common as people get older. Unlike most cancers, rates of Hodgkin lymphoma are highest among teens and young adults ages 15 to 39 years and again among older adults ages 75 years or older. White people are more likely than Black people to develop non-Hodgkin lymphoma, and men are more likely than women to develop lymphoma.

We assessed the global, regional, and national burden of HL from to , by gender, age, and social-demographic index SDI. HL incidences increased by The number of death cases and DALYs were stable. The age-standardized death rate decreased by 2. The annual age-standardized DALY rate decreased by 2. The incidence and mortality in male subjects was higher than that in female subjects.

Hodgkin lymphoma HL is a rare B cell lymphoma with 79, new cases accounting for 0. HL incidence distribution varies with age, gender, and country [ 2 ].

Significant advances in the treatment of HL mainly occurred in the s and s. During the mid-twentieth century, the status of HL changed from being an incurable disease to one of the most successfully curable diseases, leading to a sharp decline in mortality in the high-income countries [ 6 ].

Epidemiological investigations of HL have either been performed before the twenty-first century or were based mainly on the experience of the Caucasian population in developed countries, and comprehensive and latest studies on the distribution of HL in countries around the world are rare [ 7 ].

The Global Burden of Disease GBD study assessed the burden of diseases and injuries in countries and regions worldwide and provided an opportunity to comprehensively assess the distribution and development trends of HL in different countries.

More detailed data on HL incidence, mortality, DALY, and the corresponding trends in different countries is necessary and could enable policymakers to allocate limited resources and formulate policies more rationally based on this information. Therefore, we conducted this study to reveal the incidence, mortality, disability adjusted life-years DALY , and the corresponding trends of HL, according to sex, age, socio-demographic index SDI , region, and country.

We also obtained information on gender and age to assess the impact of age and gender on the burden of Hodgkin lymphoma. To further analyze the global burden of Hodgkin lymphoma, we classified location information according to three criteria. SDI is the geometric average of total fertility, per capita income, and average years of education and ranges from zero to one [ 8 , 9 ].

As shown in Tables 1 , 2 , and 3 , the world was geographically divided into 21 GBD regions to observe differences. In addition, we drew world maps including countries to observe the incidence rate, death rate and DALY of HL, and the corresponding trends in different countries from to The purpose is to exclude the influence of age composition on population incidence or mortality because the incidence or mortality of cancer varies greatly in different age stages.

Otherwise, ASR is considered to be stable. The human development index can be used as an alternative indicator of health care level in each country. All calculations were performed using R software version 3. Contrary to the The ratio of male to female incidence among different age groups in SDI, socio-demographic index. We also found that the higher the SDI, the lower the proportion of young incidence cases among all HL incidence cases, while the proportion of elderly incident cases was relatively stable Fig.

The proportion of annual young incidence cases decreased year by year, while the proportion of elderly incident cases increased year by year, as shown in Additional file 1 : Figure S4A. The peak of incidence of young incidence cases in the high SDI and high-middle SDI regions was higher than that of old patients, contrary to the peak of incidence in the middle, low-middle, and low SDI regions Additional file 1 : Figure S5. The circles represent countries that were available on SDI data.

The size of circle represents the number of Hodgkin lymphoma patients. As shown in Additional file 1 : Table S6, most countries have a bimodal age distribution. The global disease burden of Hodgkin lymphoma for both sexes in countries.

Interestingly, the higher the SDI, the lower the proportion of young deaths, while the proportion of elderly deaths increased with SDI in and Fig. The proportion of annual young deaths decreased year by year, while the proportion of elderly deaths increased year by year, as shown in Additional file 1 : Figure S4B.

As shown in Fig. The difference between young male and female subjects was that female mortality was relatively stable and even slightly decreased with age, while young male mortality had been slowly increasing with age.

On observation from the GBD regions and countries level, age-standardized DALY rate in most regions declined and no country had a rising trend. Previous epidemiological studies of HL were conducted before the twenty-first century or focused on individual or several countries [ 7 ]. We believe that our research is more comprehensive and representative due to larger and updated data.

Previous study has shown a significant increase in the incidence of HL in some populations, such as those with infectious mononucleosis or direct relatives with HD cases. For these high-risk people in high SDI countries, we believe that it is necessary to strengthen their screening for HL [ 5 ]. Although the major reason for the decline in mortality in recent decades was the improvement of treatment methods, these reductions were also due to certain human factors [ 13 ]: for instance, some histological types of HL have been reclassified as non-HL [ 14 ]; over time, pathological diagnosis of HL would tend to shift these categories to non-HL [ 15 , 16 ]; and the decline in autopsy rates would lead to a decline in incidence, as many elderly HL cases were diagnosed only after death [ 17 ].