Helicobacter pylori can it return

In the present long-term follow-up study for up to 90 months we investigated the reinfection rate of EBMT and MEA therapy, performed during — in Gyeonggi province near Seoul, and those rates are 4.

When eradication has truly been successful, reinfection is associated with the risk of re-exposure to H. Relatively low reinfection rates might be related to the decrease in prevalence of H.

Therefore, we suggest that reinfection cannot affect the choice of second-line treatment. This result might be related to the decreasing trend in eradication rate of standard triple therapy in Korea. That is, the eradication rate of per protocol PP analysis decreased up to Some studies reported that the recurrence of H. In the previous studies, the PP eradication rates were reported at Limited information exists regarding risk factors for reinfection of H.

Candidate risk factors include younger age [ 26 , 27 ], infection of close contacts [ 14 , 28 ], dental plaque [ 29 , 30 ], and contaminated endoscopic equipment [ 14 , 16 , 31 ].

Other studies did not identify any factors predictive of H. In the previous study, we reported that male gender and low income were significantly associated with reinfection of H. However, the current study did not identify any predictive factors concerning H. This study is the first study with large sample size and a long-term follow-up period in the investigation of reinfection rate of H.

However, our study has limitations. First, recrudescence cases could be included in the reinfection cases. Theoretically the fingerprinting should be performed for the differentiation of reinfected and recrudescence. However, we did not perform DNA analysis to identify the strains. In clinical practice, it is not easy to perform DNA analysis. Secondly, despite our efforts to enroll all patients, many patients dropped out from this study, and refused to receive H. In summary, in Korea, the long-term reinfection rate of H.

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Scand J Gastroenterol Suppl. J infect Dis. Dig Dis Sci. J clin Gastroenterol. Rev Esp Enferm Dig. Article Google Scholar. Pediatr Infect Dis J. Kilmartin CM: Dental implications of Helicobacter pylori. J Can Dent Assoc. J Clin Microbiol. In a single-treatment course analysis that ignored the effects of retreatment, the percentage of negative urea breath test results at 1 year was Although triple therapy appeared to be superior to the other treatments at 6 to 8 weeks, the 1-year outcomes suggest that antibiotic regimen may be less important than predictors such as treatment adherence, gender, age, and study site.

That suggests a one-size-fits-all intervention for Latin American countries may not be optimal, they wrote: "Programs will be more effective if tailored to the demographics and community ecology of their target populations. Morgan and colleagues acknowledged that the study was limited because patients were recruited from the community and the results may not be generalizable to more symptomatic patients.

Also, they did not assess the effects of antibiotic resistance, nor did they look at gastric histology. Infection with Helicobacter pylori is highly prevalent worldwide, especially in developing countries. Its presence in the gastroduodenal mucosa is related with development of peptic ulcer and other illnesses.

The eradication of H. This study was aimed to verify if H. Moreover, we sought to determine the recurrence rate. The patients were diagnosed with peptic ulcer disease, in the period of , and followed for five years or more after successful H. Patients with early recurrence - prior to five years after eradication - were excluded from the sample. During an average follow-up of 8 years, patients New ulcers appeared in two-thirds of the patients with H.

The recurrence of H. The Gram-negative spirochaete and pathogen Helicobacter pylori H. An African origin for the intimate association between humans and Helicobacter pylori. However, its role in gastrointestinal diseases was not demonstrated until , a discovery which earned Warren and Marshall a Nobel Prize in Physiology or Medicine in and rekindled interest in the study of this microorganism.

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The cost-effectiveness of population Helicobacter pylori screening and treatment: a Markov model using economic data from a randomized controlled trial. Modelling cost-effectiveness of Helicobacter pylori screening to prevent gastric cancer: a mandate for clinical trials. Save Preferences. Privacy Policy Terms of Use. This Issue. Views 22, Citations View Metrics. Twitter Facebook More LinkedIn. Original Contribution.