Ameba Ownd

アプリで簡単、無料ホームページ作成

ypovprogout1989's Ownd

Computer aided vaccine designing for influenza virus

2022.01.16 00:42




















Plasmid-only rescue of influenza A virus vaccine candidates. B , — Mueller, S. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. Shizhen, L.


Hutchinson, E. Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. Wang, Z. Live attenuated or inactivated influenza vaccines and medical encounters for respiratory illnesses among US military personnel. Coffin, J. Attenuation by a thousand cuts. Reed, L. A simple method for estimating fifty percent endpoints. Google Scholar. Quinlivan, M. Attenuation of equine influenza viruses through truncations of the NS1 protein.


Download references. The authors are indebted to A. Palese for sharing with us their 8-plasmid system for PR8, antibodies, and information.


We thank A. Paul and J. Cello for comments on the manuscript. You can also search for this author in PubMed Google Scholar. Correspondence to Steffen Mueller. Reprints and Permissions. Live attenuated influenza virus vaccines by computer-aided rational design. Nat Biotechnol 28, — Download citation.


Received : 12 March Physical biology. Spontaneous Emergence of Hierarchy in Biological Systems. Quantifying influenza vaccine efficacy and antigenic distance. Ecological and immunological determinants of influenza evolution. Epitope analysis for influenza vaccine design. Efficacy of sequential annual vaccination with inactivated influenza virus vaccine.


American journal of epidemiology. View 2 excerpts, references methods. Emerging infectious diseases. The use of vaccination to combat multiple introductions of Notifiable Avian Influenza viruses of the H5 and H7 subtypes between and in Italy. View 1 excerpt, references background. Efficacy of repeated annual immunization with inactivated influenza virus vaccines over a five year period.


Supplementary Material 1 Click here to view. References 1. Salomon R, Webster RG. The influenza virus enigma. Palese P, Shaw ML. In: Field's Virology. Knipe DM, et al. Steinhauer D, Skehel JJ. Genetics of influenza viruses. Annu Rev Genet. Maassab HF. Adaptation and growth characteristics of influenza virus at 25 degrees c.


Influenza virus-specific cytotoxic T lymphocytes: a correlate of protection and a basis for vaccine development. Curr Opin Biotechnol. Sant AJ, et al. Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design. Expert Rev Vaccines. Hikono H, et al. T-cell memory and recall responses to respiratory virus infections. Immunol Rev. Swain SL, et al. Simonsen L, et al. Impact of influenza vaccination on seasonal mortality in the US elderly population.


Arch Intern Med. Live attenuated influenza A virus vaccines in children: results of a field trial. J Infect Dis. Belshe RB, et al. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. N Engl J Med. Coleman JR, et al. Virus attenuation by genome-scale changes in codon pair bias.


Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template. Nonrandom utilization of codon pairs in Escherichia coli. Moura G, et al. Large scale comparative codon-pair context analysis unveils general rules that fine-tune evolution of mRNA primary structure. Synthetic viruses: a new opportunity to understand and prevent viral disease. A DNA transfection system for generation of influenza A virus from eight plasmids.


Schickli JH, et al. Plasmid-only rescue of influenza A virus vaccine candidates. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity.


J Virol. Shizhen L. Bencao Gangmu: Compendium of Materia Medica. Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus.


Live attenuated or inactivated influenza vaccines and medical encounters for respiratory illnesses among US military personnel. Coffin JM. Attenuation by a thousand cuts. Quinlivan M, et al. Attenuation of equine influenza viruses through truncations of the NS1 protein. Reed LJ, Muench M. A simple method for estimating fifty percent endpoints. Am J Hyg. Full text links Read article at publisher's site DOI : Smart citations by scite. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles.


Explore citation contexts and check if this article has been supported or disputed. Wikipedia 2. Data Data behind the article This data has been text mined from the article, or deposited into data resources. BioStudies: supplemental material and supporting data. Nucleotide Sequences Showing 8 of 8.


Show less. Faculty Opinions 2. Similar Articles To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation. Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice.


Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate.


Access full text. Related articles Lyme Disease and Relapsing Fever Spirochetes. Climate Change and Microbial Ecology.