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- Malaria Immunology: Targeting the Surface of Infected Erythrocytes
- Page: 596
- Format: pdf, ePub, mobi, fb2
- ISBN: 9781071621882
- Publisher: Springer US
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This volume covers a broad range of methods, technologies, and prools on malaria. Chapters detail research on collecting parasites in the field, single molecule-level analyses of adhesive interactions, and focused studies aiming at disrupting the devastating disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible prools. Authoritative and cutting-edge, Malaria Immunology: Targeting the Surface of Infected Erythrocytes aims to be a useful and practical guide to researches to help further their study in this field. Chapter Analysis of var gene transcription pattern using DBLα-tags [Chapter 14] is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Expanding the antimalarial toolkit: Targeting host–parasite
In particular, P. falciparum exports proteins to the erythrocyte surface that However, broad immunity against severe malaria develops quickly in early
the antibody-mediated immune response to malaria - Cell Press
immunity to P. falciparum malaria had merozoites) are their main targets [.
Plasmodium falciparum-infected erythrocytes: agglutination by
surface antigens (VSAs) of Plasmodium falciparum-infected red blood cells are potentially important targets of naturally acquired immunity to malaria.
Malaria vaccines since 2000: progress, priorities, products
Pre-erythrocytic vaccines (PEV) target antigens from The first malaria gene to be cloned encodes the major surface
Vaccine candidate discovery for the next generation of malaria
The need for a highly effective malaria vaccine remains urgent. on the infected red cell surface are targets for naturally acquired immunity to malaria.
Malaria prevention: from immunological concepts to effective
This immunity is mediated largely by antibodies that target Plasmodium antigens on the RBC surface that facilitate adhesion and allow the
Comprehensive analysis of antibody responses to - PubMed
on the surface of merozoites and infected erythrocytes play an important role in protective immunity to Plasmodium falciparum malaria.
World Malaria Day 2009 - NCBI
Immunity to the pre-erythrocytic stage of the of malarial infection is a viable vaccine target?
Malaria Immunology: Targeting the Surface of - Google Books
Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Front Cover. Anja Tatiana Ramstedt Jensen, Lars Hviid.
Failure to respond to the surface of Plasmodium - PubMed
Following infection with Plasmodium falciparum malaria, children in endemic areas develop antibodies specific to antigens on the parasite-infected red cell
Adhesion of Plasmodium falciparum-infected erythrocytes to
Severe malaria has a high mortality rate (15–20%) despite treatment with effective antimalarial drugs. Adjunctive therapies for severe malaria that target
The Outcomes of Antibody-Dependent Complement Activation
Some of the major targets of acquired immunity to blood-stage infection are the surface antigens on P. falciparum-IEs (60). Parasite antigens on
Antibody Targets on the Surface of Plasmodium - NCBI
Antibody Targets on the Surface of Plasmodium falciparum–Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young
Beyond Binding: The Outcomes of Antibody-Dependent
Antibody immunity against malaria is effective but non-sterile. of infected erythrocytes towards antibody-mediated complement lysis,
Malaria Parasites: The Great Escape | Immunology - Frontiers
As the infection progresses, the number of RBC decreases and this may lead Antibodies targeting the surface antigens are thought to act
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